Patient: Dr. Gulati, I’ve failed three IUI cycles, and I’m wondering if you could do the IUI cycle again for me. Maybe the previous doctor wasn’t very good, or because you’re a specialist, you might have had better success. What do you think?
Dr. Gulati: I understand your concern and your reluctance to move on to more expensive treatments like IVF. However, if you’ve completed three IUI cycles in a good clinic without success, changing the doctor is unlikely to increase your chances.
Patient: So, you’re saying that trying another IUI cycle might not help?
Dr. Gulati: Exactly. There needs to be a boundary, or a “Lakshman Rekha,” in fertility treatments. If pregnancy hasn’t occurred after three IUI cycles, the likelihood of success diminishes with each additional cycle. While it’s not impossible to conceive in the fourth or fifth IUI cycle, the chances are quite low.
Patient: But isn’t there still a chance? Why not try one more time?
Dr. Gulati: While you can attempt a fourth or fifth IUI cycle, it’s important to understand that the probability of success continues to decrease. Repeated failed attempts can lead to frustration, financial strain, and a loss of confidence in both your doctors and yourself.
Patient: That sounds discouraging. Is there a better alternative?
Dr. Gulati: Yes, and this is where the concept of opportunity cost comes into play. By persisting with additional IUI cycles, you might miss out on the higher success rates offered by IVF. With IVF, we have more control over the process since we create the embryo in the lab rather than leaving it up to nature. This is why pregnancy rates with IVF are significantly higher than with IUI.
Patient: So, you think I should consider IVF instead of continuing with IUI?
Dr. Gulati: Exactly. If you’ve failed three complete IUI cycles in a reputable clinic, it’s time to seriously consider transitioning to IVF. Persisting with IUI by switching doctors isn’t the best approach. IVF offers a much better chance of success and can save you the emotional and financial toll of repeated IUI failures.
Patient: I see. The cost of IVF is a concern, though.
Dr. Gulati: I understand, but consider the bigger picture. While the initial cost of IVF is higher, the overall cost might be lower when you factor in the repeated IUI cycles and the associated emotional distress. IVF can increase your likelihood of achieving pregnancy dramatically, making it a worthwhile investment.
Patient: This is very helpful, Dr. Gulati. Thank you for your advice.
Dr. Gulati: “You’re very welcome! If you need more details or personalized guidance, feel free to visit my website at www.eggdonors4all.com.”

Dr. Pooja Patel is a Chief Surrogacy Coordinator at Surrogacy4all. She has 10 years of experience in Anesthesiology and critical care medicine.
She received her medical degree from Seth GS Medical College and K.E.M Hospital in India. She then completed an internship. She finished her Anesthesia residency at Grant Govt Medical College and JJ Group of Hospitals in India.
Egg donation is a process where a woman (the egg donor) provides one or several eggs (also known as oocytes) for purposes of assisted reproduction, with the eggs being fertilized in the laboratory. Once fertilized, the resulting embryos are transferred to the recipient’s uterus to initiate a pregnancy, or they can be cryopreserved (frozen) for future use.
Licensed & Registered: NYS Surrogacy Program License GSP220903 · NYS Tissue Bank License ID 1570 · California Tissue Bank License CTB00082276 · Maryland Tissue Bank License TB3527 · FDA HCT/P Establishment Registration FEI 3021544308 · Health Canada Establishment Registration 000119
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